Generic Name: acetaminophen and hydrocodone (ah see ta MIH no fen and hye dreo KOE done)
Brand Names: Anexsia, Anolor DH5, Bancap HC, Dolacet, Lorcet 10/ 650, Lorcet HD, Lorcet Plus, Lortab, Lortab 10, Lortab 5/ 500, Lortab 7.5/ 500, Lortab Elixir, Norco, T-Gesic, Vicodin , Vicodin ES, Vicodin HP, Zydone

What is acetaminophen and hydrocodone?
• Hydrocodone (related to codeine) is in a class of drugs called narcotic analgesics. It relieves pain.
• Acetaminophen is a less potent pain reliever that increases the effects of hydrocodone.
• Together, acetaminophen and hydrocodone are used to relieve moderate-to-severe pain.
• Acetaminophen and hydrocodone may also be used for purposes other than those listed in this medication guide.

How should I take acetaminophen and hydrocodone?
• Take acetaminophen and hydrocodone exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Take acetaminophen and hydrocodone with food or milk if it causes stomach upset.
• To ensure that you get a correct dose, measure the liquid form of acetaminophen and hydrocodone with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
• Hydrocodone is habit forming. It is possible become physically and/ or psychologically dependent on the medication. Do not take more than the prescribed amount of medication or take it for longer than is directed by your doctor. Withdrawal effects may occur if acetaminophen and hydrocodone is stopped suddenly after several weeks of continuous use. Your doctor may recommend a gradual reduction in dose.
• Acetaminophen and hydrocodone may cause constipation. Drink plenty of water (six to eight full glasses a day) to lessen this side effect. Increased fiber in the diet may also help to alleviate constipation.
• Store acetaminophen and hydrocodone at room temperature away from moisture and heat.

What happens if I miss a dose?
• Take the missed dose as soon as you remember. Do not take a double dose of this medication. Wait the prescribed amount of time before taking the next dose.

What happens if I overdose?
• Seek emergency medical attention if an overdose is suspected.
• Symptoms of an acetaminophen and hydrocodone overdose may include slow breathing, seizures, dizziness, weakness, loss of consciousness, coma, confusion, tiredness, cold and clammy skin, small pupils, nausea, vomiting, and sweating.

What should I avoid while taking acetaminophen and hydrocodone?
• Avoid alcohol while taking acetaminophen and hydrocodone. Alcohol can increase drowsiness and dizziness caused by the medication, possibly resulting in unconsciousness and death. Also, acetaminophen can be damaging to the liver when taken with alcohol.
• Acetaminophen and hydrocodone may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if acetaminophen and hydrocodone is taken with any of these medications. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.
• Use caution when driving, operating machinery, or performing other hazardous activities. Hydrocodone may cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities.
• Other products may also contain acetaminophen, especially over-the-counter pain, fever, cold, and allergy medications. Do not take any other products that contain acetaminophen without first talking to your doctor. Too much acetaminophen can be dangerous.

What are the possible side effects of acetaminophen and hydrocodone?
• If you experience any of the following serious side effects, stop taking acetaminophen and hydrocodone and seek emergency medical attention or contact your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
· slow, weak breathing;
· seizures;
· cold, clammy skin;
· severe weakness or dizziness;
· unconsciousness;
· yellowing of the skin or eyes; or
· unusual fatigue, bleeding, or bruising.
• Other, less serious side effects may be more likely to occur. Continue to take acetaminophen and hydrocodone and talk to your doctor if you experience
· constipation;
· dry mouth, nausea, vomiting, or decreased appetite;
· dizziness, tiredness, or lightheadedness;
· muscle twitches;
· sweating;
· itching;
· decreased urination; or
· decreased sex drive.
• Hydrocodone is habit forming. It is possible become physically and/ or psychologically dependent on the medication. Do not take more than the prescribed amount of medication or take it for longer than is directed by your doctor. Withdrawal effects may occur if acetaminophen and hydrocodone is stopped suddenly after several weeks of continuous use. Your doctor may recommend a gradual reduction in dose.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect acetaminophen and hydrocodone?
• Do not take acetaminophen and hydrocodone if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. Dangerous side effects could result.
• Acetaminophen and hydrocodone may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if acetaminophen and hydrocodone is taken with any of these medications. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.
• Other products may also contain acetaminophen, especially over-the-counter pain, fever, cold, and allergy medications. Do not take any other products that contain acetaminophen without first talking to your doctor. Too much acetaminophen can be dangerous.
• Drugs other than those listed here may also interact with acetaminophen and hydrocodone. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?
• Your pharmacist has additional information about acetaminophen and hydrocodone written for health professionals that you may read.